Syracuse vs. Virginia odds, prediction, line, spread: 2022 Week 4 college football picks based on sample in run 51-43


The ACC foes square off in prime time Friday at the JMA Wireless Dome when the Syracuse Orange host the Virginia Cavaliers in the fourth game of the 2022 season for both programs. This is the sixth all-time meeting between the conference rivals, with Virginia leading the all-time series 3-2 after three straight wins. Syracuse is 3-0 on the season, while UVA enters 2-1 overall. Syracuse is 3-0, Virginia 0-3 against the spread in 2022.

Kickoff is at Syracuse at 7pm ET. Caesars Sportsbook lists the Orange as a 9-point home favorite, while the latest Virginia vs. Syracuse odds have a 54-point over/under, or total points that Vegas thinks they’ll score. Before you make your Virginia vs. Syracuse picks, You should check out college football predictions and betting tips from SportsLine’s advanced computer simulation model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated more than $3,300 in profits for $100 players at its best. College football picks Against the spread. It enters Week 4 of the 2022 college football season at 51-43, the top-rated college football spread among all pre-2021 money-line picks. Anyone who has followed this has received great income.

Now, the model has set its sights Virginia vs. Syracuse And locked in its picks and CFB projections. You can now head over to SportsLine to check out the model’s choices. Now, here are several College Football Odds and Syracuse vs. Betting Lines for UVA:

  • Virginia vs. Syracuse Spread: Syracuse -9
  • Virginia vs. Syracuse Over/Under: 54 points
  • Virginia vs. Syracuse Money Line: Syracuse -355, Virginia +278
  • VIR: Cavaliers are 7-8 in their last 15 games against the spread
  • SYR: Orange are 11-4 in their last 15 games against the spread
  • Virginia vs. Syracuse Picks: Check out the selections here

Special game | Syracuse Orange vs. Virginia Cavaliers


Virginia can hide why

Virginia’s offense has sky-high upside. The Cavaliers have surpassed 500 total yards in two of three games this season, and Virginia has a strong ground attack. Virginia averages 180 rushing yards per game and 4.6 yards per carry, with quarterback Brennan Armstrong bringing a dual-threat. Armstrong has over 1,000 career rushing yards and is coming off a 2021 season in which he produced 4,449 passing yards and 31 touchdowns.

On the outside, Virginia has an intriguing and dynamic threat in Keaton Thompson. He caught 78 passes for 990 yards last season and has 18 catches for 235 yards in three games in 2021. Thompson rushed for more than 230 yards on 39 carries in 2021, and he’s difficult to contain for oppositions. Virginia also faces a Syracuse defense that’s allowed a 73.5% completion rate through three games, and the Cavaliers are well-coached and won’t be overly affected by the road environment at Syracuse.

Why Syracuse can hide

Syracuse is set to begin the 2022 season. The Orange are 3-0 for the first time since 2018, with two of those wins coming against Power Five opponents. Syracuse is cooking on offense, averaging 9.0 yards per pass attempt with eight passing touchdowns and no interceptions. The Orange excels on third down, converting 44.1% of its chances, and Syracuse has a top-end running back in Sean Tucker. Tucker led the ACC in rushing last season, racking up nearly 1,500 rushing yards and 12 touchdowns, and he has 254 yards and two touchdowns on the ground in 2022.

Tucker has 12 catches for 124 yards through the air, and quarterback Garrett Schrader is a dual threat with over 700 passing yards and 200 rushing yards with 11 combined touchdowns in three games. With Syracuse holding opponents to less than 17 points per game, the Orange can be confident in a rough situation in front of their home fans.

How to make Virginia vs. Syracuse picks

SportsLine’s model leans under the point total, with both teams projected to throw at least one interception. The model also states that one side of the spread hits in more than 50% of the simulations. You can only see Model’s CFB picks on SportsLine.

So who wins Virginia vs. Syracuse? And which side does the spread hit in more than 50% of the simulations? Visit SportsLine for the Virginia vs. Syracuse spreadAnd find out.



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